Kcnq1 Gain-of-function Mutation In Familial Atrial Fibrillation

Correspondence - Circulation
Structural remodeling in atrial fibrillation. J Am Coll Cardiol. 2003;41: 2197–2204. 3. Huang W. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251–254. (Circulation. 2006;114:e566.) © 2006 American Heart Association, Inc. ... Fetch Here

Screening Of The Ito Regulatory Subunit Klf15 In Patients ...
Al. (2003). KCNQ1 gain-of-function mutation in familial atrial fibrilla-tion. Science 299, 251–254. Christophersen, I. E., Olesen, M. S., Liang, B., Andersen, M. N., Larsen, Screening of the Ito regulatory subunit Klf15 in patients with early-onset lone atrial fibrillation ... Visit Document

Overview Genetics Of Atrial Fibrillation: Towards Subtype And ...
Genetics of Atrial Fibrillation: Towards Subtype and Mechanism-Based Therapies atrial fibrillation Age, yr. <5 5-9 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85-89 90-94 >95 Population with AF x 1000 500 400 300 200 100 0 U.S. population U ... Read More

Lundby et al KCNQ1 Mutation Q147R and Atrial Fibrillation 1535. plexes elicited the slowly activating voltage-dependent K currents (Figures 3A and 3B, and Table 1). However, the gain-of-function mutation in familial atrial fibrillation. ... Read Content

Etd.library.vanderbilt.edu
Iv ACKNOWLEDGEMENTS This work would not have been possible without the financial support of the Greater Southeast Affiliate Predoctoral Fellowship 11PRE7610043 from the American H ... Visit Document

Genetic Testing ForCardiovascular Disorde Rs Familion About ...
114:119-25. 3. Lubitz SA, Yin X, Fontes JD, et al. Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. JAMA Chen YH, Xu WJ, Bendahhou S, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251-4. 6. Yang Y ... View Doc

Mechanistic Basis For Atrial And Ventricular Arrhythmias ...
Mechanistic Basis for Atrial and Ventricular Arrhythmias Caused by KCNQ1 Mutations Daniel C. Bartos familial atrial fibrillation, and a gain-of-function phenotype has been implicated to This was the first study linking a known LQT1 mutation to familial AF. ... Fetch Content

New Insights into the Molecular Basis of Atrial Fibrillation 1. Introduction Atrial fibrillation Xu SJ, Bendahhou S, Wang XL, Wang Y, Xu WY et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251–254. 14. Yang Y, Xia M, Jin Q, Bendahhou S, Shi ... Read Here

Lasse S. Ravn, MD NIH Public Access *,†,‡,¶, §, Guido D ...
Herron KJ, Ballew JD, et al. Familial atrial fibrillation is a genetically heterogeneous disorder. J Am Coll Cardiol 2003;41:2185–2192. 11. Chen YH, Xu SJ, Bendahhou S, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251–254. [PubMed: 12522251] ... View Document

A KCNQ1 mutation Causes Age-dependant Bradycardia And ...
A KCNQ1 mutation causes age-dependant bradycardia physiology showed that V241F mutation in KCNQ1 shifted Electrophysiology .Ionchannel .KCNQ1 .Mutation Introduction Atrial fibrillation (AF) is the most common sustained tachy- ... Get Content Here

Familial Atrial Fibrillation: Simulation Of The Mechanisms ...
Atrial Fibrillation (AF) is an abnormal rapid activation of the atrial muscle, Huang W. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251–254. [3] Courtemanche M, Ramirez RJ, Nattel S. Ionic mechanisms ... Get Doc

KCNE2 - Wikipedia, The Free Encyclopedia
KCNQ1-KCNE2 is required for optimal iodide uptake into the thyroid by the basolateral sodium iodide symporter KCNE2 is also associated with familial atrial fibrillation, which may involve excessive KCNQ1-KCNE2 current caused by KCNE2 gain-of-function mutations. [13] ... Read Article

Structural Models For The KCNQ1 Voltage-Gated Potassium Channel
Structural Models for the KCNQ1 Voltage-Gated Potassium Channel familial atrial fibrillation, Barhanin, J., and Huang, W. (2003) KCNQ1 gain-of-function mutation in familial atrial fibrillation, Science 299, 251-254. 17. ... Read Content

Characterization Of A Chinese KCNQ1 mutation (R259H) That ...
Characterization of a Chinese KCNQ1 mutation (R259H) Conclusions R259H is a gain-of-function muta-tion of the KCNQ1 channel that is responsible for SQTS2. KCNQ1 in familial atrial fibrillation without a QT abnor-mality. Then, ... Read Here

ATRIAL FIBRILLATION IN CHILDHOOD WITH FAMILIAL ...
ATRIAL FIBRILLATION IN CHILDHOOD WITH FAMILIAL HYPERTHYROIDISM IN AFRO-CARIBBEANS familial atrial fibrillation. N Engl J Med. 1997;336:905–11. 3. Chen YH, Xu SJ, Bendahhou S, Wang XL, Wang Y, Xu WY, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science. 2003; ... Fetch Doc

Characterization Of KCNQ1 atrial fibrillation mutations ...
Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1 Priscilla J. Chan, Jeremiah D. Osteen, Dazhi Xiong, Michael S. Bohnen, Darshan Doshi,2 KCNQ1 gain-of-function mutation in familial atrial fibrillation. ... Get Document

Short Communication
6. Chen Y-H, Xu S-J, Bendahhou S, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003; 299: 251-254. 7. Bendahhou S, Marionneau C, Haurogne K, et al. ... View Doc

Gene-guided Therapy For Catheter-ablation Of atrial ...
Gene-guided therapy for catheter-ablation of atrial fibrillation: arewethereyet? Henry Huang1 & Dawood Darbar1 Received: 23 November KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science, 299,251–4. 6. Gudbjartsson,D.F.,Arnar,D.O.,Helgadottir, A.,Gretarsdottir,S., Holm ... Document Viewer

Original Paper Cellular Physiology - Karger Publishers
Original Paper Cellular Physiology Cell Physiol Biochem 2012;29:809-818 Accepted: April 11, S140G KCNQ1 atrial fibrillation mutation affects “I(KS) KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251-254. 19 Johnson JN, Tester DJ, ... Retrieve Here

Gain Of Function InKs Isecondary To A mutation InKCNE5 ...
Isecondary to a mutation inKCNE5 associated with atrial fibrillation resulting in gain of function of KCNQ1–the Chen YH, Xu SJ, Bendahhou S, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 2003;299:251–254. 12. Yang Y, Xia M, ... Access Content